Kakarla V Chalam Selected Research

Bevacizumab (Avastin)

1/2014	Aqueous interleukin-6 levels are superior to vascular endothelial growth factor in predicting therapeutic response to bevacizumab in age-related macular degeneration.
1/2013	Bevacizumab inhibits proliferation of choroidal endothelial cells by regulation of the cell cycle.
1/2011	Freezing adversely affects measurement of vascular endothelial growth factor levels in human aqueous samples.
1/2011	Evaluation of cytotoxicity of bevacizumab on VEGF-enriched corneal endothelial cells.
12/2010	Bevacizumab suppression of establishment of micrometastases in experimental ocular melanoma.
4/2009	Evaluation of cytotoxic effects of bevacizumab on human corneal cells.

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Kakarla V Chalam Research Topics

Disease

15	Macular Degeneration (Age-Related Maculopathy) 11/2021 - 07/2010
11	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2019 - 05/2003
7	Macular Edema 01/2019 - 06/2005
6	Glaucoma 11/2021 - 12/2007
5	Retinal Detachment (Retinal Detachments) 11/2021 - 01/2010
5	Cataract (Cataracts) 05/2013 - 07/2004
4	Retinal Diseases 01/2022 - 01/2011
4	Choroidal Neovascularization 09/2013 - 01/2012
3	Ischemia 08/2016 - 01/2011
3	Neovascular Glaucoma 11/2014 - 09/2002
3	Ganglion Cysts (Ganglion) 09/2013 - 06/2008
3	Hypoxia (Hypoxemia) 01/2013 - 01/2012
2	Choroidal Effusions 09/2020 - 01/2008
2	Sickle Cell Anemia (Hemoglobin S Disease) 08/2016 - 11/2013
2	Inflammation (Inflammations) 04/2016 - 05/2003
2	Blindness (Hysterical Blindness) 06/2013 - 05/2013
2	Retinal Vein Occlusion 01/2011 - 06/2005
2	Open-Angle Glaucoma (Glaucoma, Open Angle) 01/2011 - 06/2008
1	Polypoidal Choroidal Vasculopathy 09/2021
1	Endophthalmitis (Ophthalmia) 09/2020
1	Retinal Degeneration 01/2017
1	Optic Neuritis (Retrobulbar Neuritis) 01/2017
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2016
1	Wet Macular Degeneration 01/2014
1	Pulmonary Arterial Hypertension 11/2013
1	Retinal Artery Occlusion 11/2013
1	Neoplasms (Cancer) 01/2013
1	Retinal Perforations 09/2012
1	Necrosis 06/2011
1	Melanoma (Melanoma, Malignant) 12/2010
1	Neoplasm Micrometastasis 12/2010
1	Proliferative Vitreoretinopathy 12/2009
1	Hemangioma (Angioma) 09/2009
1	Retinal Neovascularization 04/2009
1	Corneal Neovascularization 04/2009
1	Aplastic Anemia (Anemia, Hypoplastic) 11/2008
1	Wounds and Injuries (Trauma) 07/2008

Drug/Important Bio-Agent (IBA)

17	Retinaldehyde (Retinal)IBA 01/2022 - 03/2009
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2014 - 04/2009
6	Bevacizumab (Avastin)FDA Link 01/2014 - 04/2009
3	Fluorescein (Funduscein)FDA LinkGeneric 11/2017 - 01/2012
3	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2011
3	Retinal Pigments (Pigments, Visual)IBA 09/2013 - 12/2009
2	SirtuinsIBA 01/2017 - 06/2012
2	Biological ProductsIBA 01/2017 - 04/2016
2	ResveratrolIBA 04/2016 - 01/2013
2	Coloring Agents (Dyes)IBA 11/2014 - 06/2011
2	ZeaxanthinsIBA 06/2014 - 05/2013
2	LuteinIBA 06/2014 - 05/2013
2	CytokinesIBA 01/2014 - 01/2011
2	Pharmaceutical PreparationsIBA 01/2013 - 01/2011
2	Protein Isoforms (Isoforms)IBA 01/2013 - 01/2011
2	cobaltous chloride (cobalt(II)chloride)IBA 01/2013 - 01/2012
2	Sirtuin 1IBA 06/2012 - 01/2012
1	FluorocarbonsIBA 11/2021
1	Silicone OilsIBA 11/2021
1	1-phenyl-3,3-dimethyltriazene (PDT)IBA 09/2021
1	Prednisone (Sone)FDA LinkGeneric 09/2021
1	SteroidsIBA 09/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 09/2020
1	Endothelial Growth FactorsIBA 01/2019
1	afliberceptIBA 01/2019
1	Angiotensin-Converting Enzyme 2IBA 01/2018
1	ProteomeIBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Messenger RNA (mRNA)IBA 11/2014
1	Interleukin-6 (Interleukin 6)IBA 01/2014
1	Tadalafil (Cialis)FDA Link 11/2013
1	Phosphodiesterase 5 InhibitorsIBA 11/2013
1	CobaltIBA 09/2013
1	Protons (Proton)IBA 09/2013
1	ImmunosorbentsIBA 01/2013
1	EnzymesIBA 01/2013
1	Ranibizumab (Lucentis)FDA Link 09/2012
1	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 09/2012
1	Protein Kinase CIBA 06/2012
1	JNK Mitogen-Activated Protein KinasesIBA 06/2012
1	Caspase 3 (Caspase-3)IBA 06/2012
1	Erythropoietin FDA Link 01/2012
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2012
1	sirtinolIBA 01/2012
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 07/2010
1	Triamcinolone (Aristocort)FDA Link 01/2010
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 08/2009

Therapy/Procedure

9	Vitrectomy 11/2021 - 07/2004
5	Lasers (Laser) 01/2019 - 03/2009
4	Light Coagulation 01/2019 - 03/2009
3	Therapeutics 01/2013 - 01/2008
2	Photochemotherapy (Photodynamic Therapy) 09/2021 - 09/2009
2	Slit Lamp 01/2019 - 08/2016
2	Contact Lenses 01/2019 - 07/2004
2	Intravitreal Injections 01/2011 - 05/2003
1	Injections 01/2019
1	Phacoemulsification 01/2015
1	Aftercare (After-Treatment) 09/2012
1	Proton Therapy 03/2012
1	Scleral Buckling 01/2010
1	Corneal Transplantation (Keratoplasty) 04/2009
1	Platelet Transfusion (Blood Platelet Transfusions) 11/2008